Molecular Diagnostics — DU B. Sc. (Hons) Biochemistry Previous Year Question Papers

There are 6 questions: 1. (a) Explain the following terms : (i) Risk Markers (ii) Acute graft rejection (iit) Autograft (b) Name a molecular marker for Diabetes. 14,1 (a) Explain the Good Lab Practices to handle biomedical waste. (b) Explain the risk factors that would mandate a BSL-3 and BSL-4 lab facility. (c) Explain the molecular méthods used in the diagnosis of the follówing diseases : .3. Give important molecular markers for the following diseases and their importance: (a) Cardiac markers (6) Inflammation markers (c) Tumor markers 4. (a) Give the different sources of stem cells for stem cells transplantation. (b) Differentiate between MHC class I and MHC class II antigens. • (c) Briefly explain the significance of HLA typing in organ transplantation. 5. (a) What is the Pre-conception and Pre-Natal Diagnostic Techniques (PCPNDT) Act? Why was it formulated? (b) Explain the prenatal maternal serum triple test and its significance in the diagnosis of Down syndrome. (e) What are the various indications for prenatal testing ? 5,5,5. Explain the role of the following Techniques in Diagnostics :