Medicines in Daily Life — DU B.Sc (hons) Chemistry Previous Year Question Papers

Medicines in Daily Life 1. (a) Objective type questions (choose the correct option) : i. Aspirincontains as its pharmacologically active compound: (b) Acetylsalicylic acid (d) Morphine ii. iii. 1V. V. A scientific tool used for identification of new drug targets is: (a) Molecular modelling (c) Structure-activity relationship analysis (d) All of these The concept and term `chemotherapy' was originally proposed by: (a) Alexander Fleming (b) Paul Ehrlich (c) Edward Jenner (d) Robert Koch Health is best described as: (a) Merely absence of illness (b) A state of complete physical, mental and social wellness (c) Only bodily fitness (d) Ability to fight infections The biological process through which a drug is removed from the body is called: , (b) Fill in the blanks: 1' ii. act as an Anticaogulant drug. isomer of cetirizine is more active. Sodium nitrite is used as an antidote against (c) Write short notes on Health, Disease, and Drug, along with appropriate examples. (5,5,5) 2. (a) Define chemotherapy. Discuss its basic principles and explain why it plays a crucial role in modern medical treatment. (b) Explain Structure-Activity Relationship (SAR) and discuss its significance in improving drug molecules. (c) Discuss the challenges of drug discovery? (5,5,5) 3. (a) Write the chemical structure, synthesis, uses and adverse effects of Aspirin. (b) Identify the common structural ring/moiety present in both Norfloxacin and (c) Describe the chemical structures and uses of Morphine and Codeine, and state their major side effects. 4. (a) Write the drug class .and a.ctive ingroedient of Albendazole. Mention the natural remedies used in place of this drug. (b) What are antacids? Describe their ideal characteristics. Give the names and che'mical structures of any two antacid drugs. (c) Explain the role of vitamins and dietary supplements in maintaining overall health. 5. (a) Describe the natural sources known to exhibit blood-pressure-lowering activity, and mention their bioactive components. (b) Explain antidepressant drugs. Write two examples. Also describe natural approaches used to manage depression. (c) Write the chemical structure, synthetic route, and therapeutic applications of paracetamol. (5, 5,5) 6. (a) Write the uses, possible adverse.reactions, and natural substitutes for Fluconazole. (b) Describe the therapeutic uses, natural substitutes, and adverse reactions of the diuretic medicine Lasix (Furosemide). (c) Write short notes on any two of the following: (i) Antidiabetic drugs (ii) Classification of drug