Advances in Microbiology — DU B. Sc. (Hons) Microbiology Previous Year Question Papers

1. (a) Briefly explain the following (any six) : 1.5x6=9 (i) System biology (it) Effector protein. (v) Interaction network (vi) Multidrug efflux system 6a 92l-2r7 51 US: 161 (vii) Viral zoonosis. (b) Write the contribution of the following scientists (any three : 2. (a) Differentiate between the following (any two) : (i) Core and flexible genomes (ii) Autoinducers of Gram-positive and Gram-negative bacteria (iti) Sequence-based and function-based metagenomics. (b) Expand the following terms (any four) : (iii) PAM 3. (a) What are virus-like nanoparticles? Discuss their role in health care and (b) Explain type-III secretion system using a suitable microbial system. 6 4. (a) Define viral zoonosis with suitable examples. What are the key factors that contribute to the emergence and spread of pandemics? 6 (b) What are biofilms ? Discuss the role of phages in treating biofilm infections. 6 5. (a) What are pathogenicity islands ? Give an example. Explain their different properties. 6 (b) What do you mean by synthetic biology? Discuss its potential applications with suitable examples. 6 6. Write short notes on the following (any three) : 4×3=12 (i) Hypersensitive response (iti) Biological networks (io) CRISPR-Cas.