Nutritional Biochemistry-II — DU B.Sc. (Hons.) Home Science Previous Year Question Papers

1. A. Justify the following: i. Enzymes reduce the activation-energy of biochemical reactions. ii. Michaelis-Menten equation helps to understand enzyme kinetics. iii. Gluconeogenesis is essential during fasting. iv. B-oxidation is a major pathway of fatty acid degradation V. Urea cycle prevents ammonia toxicity. (2x5=10) B. Define the following: i. Allosteric enzymes ii. Active site iii. Vmax iv. Ketogenesis il. 94 4 (Active site) 2. Differentiate between the following: A. Hexokinase and Glucokinase B. Glycolysis and Citric Acid Cycle C. Ketogenesis and Ketosis D. Transamination and Deamination E. Purine catabolism and Pyrimidine catabolism (3×5=15) 3. Write the reactions for the following conversions: A. Glycogen into Glucose-1-phosphate B. Phosphoenolpyruvate into Pyruvate C. Hypoxanthine into Uric acid D. Oxaloacetate into Aspartate E. Glutamate into Glutamine (3×5=15) 4. A. Explain the effect of substrate concentration on enzyme activity. B. Write down the bypass reactions of gluconeogenesis. C. Discuss the metabolic role of glycogenolysis. (5, 6, 4) 5. A. Explain the role of carnitine shuttle in fatty acid oxidation. B. Describe the steps of the urea cycle. C. Discuss the amphibolic nature of citric acid cycle. (4,9,2) 6. Write short notes: B. Control of blood glucose - C. Ketone bodies D. Structure and function of nucleotides E. Significance of pentose phosphate pathway (3 × 5=15)