Nanobiotechnology — DU B.Sc. (Hons.) Zoology Previous Year Question Papers

based drug delivery. Differentiate between active L and passive targeting. (7) 5. (a) Explain the role of lipid nanoparticles and viral Semester : VI (NEP-UGCF) 6. (a) Describe nanotoxicity with reference to the effect of this question paper. 3. Draw well-labelled diagrams wherever necessary. (b) Explain genotoxicity, carcinogenicity and the methods used for evaluation of nanoparticle toxicity. (7) 7. Write short notes on any three of the following : (3x5=15) (a) Define the following : (5x2=10) (a) Ball milling (i) Nanoscale assembly (b) Intranasal drug delivery (i) Lipid nanoparticle vaccine (d) Environmental nanoremediation technology (e) Risk assessment of nanoparticle exposure (b) Differentiate between the following : (4x2=8) (iii) Iron oxide nanoparticles are commonly used in - - imaging. (i) Bulk materials and nanomaterials (i) Chemical synthesis and green synthesis of (iv) The harmful effect of nanoparticles on cells nanoparticles is called (iii) Oral drug delivery and controlled drug release (e) Match the following : (4x1=4) (iv) Enzyme-based biosensor and nano-immunosensor Column A Column B (c) State whether the following statements are True (i) Quantum dots (a) Passive tumour accumulation or False : (4x1=4) (ii) Carbon nanotubes (b) Fluorescent imaging probe (iii) Nanofiltration (c) Removal of pollutants/ (i) Quantum dots exhibit size-dependent optical membrane pathogens from wastewater properties. (iv) EPR effect (d) One-dimensional carbon (ii) Active targeting does not require any ligand nanostructure on the nanoparticle surface. 2. (a) Explain biomaterials and synthetic materials used (iii) Nanofiltration is useful for removal of in nanobiotechnology. (7) organics, inorganics and pathogens from liposomes, polymeric micelles, quantum dots, iron (iv) Smaller nanoparticles may show greater nanoparticles and carbon nanotubes, with their cellular uptake than larger particles of the applications. (8) same material. 3. (a) Discuss top-down and bottom-up approaches used (d) Fill in the blanks : (4x1=4) in the nanofabrication of nanobiomaterials. (7) (i) Liposomes are composed of a - - bilayer. (b) Explain chemical synthesis of metal oxide (ii) Ball milling is an example of a nanoparticles and co-precipitation methods with approach. suitable examples. (8)