Principles of Genetics — DU B. Sc. (Hons) Microbiology Previous Year Question Papers

Q4 (a) Colour blindness is an X-linked recessive trait. A carrier female marries a normal male. Calculate the probability of: (2+2=4) (i) Colour-blind son (ii) Carrier daughter (b) Explain factors disturbing Hardy-Weinberg equilibrium. Discuss the applications of Hardy-Weinberg law in population genetics. (8) Q 5 (a) Discuss the experimental design and outcome of Mendel's monohybrid and dihybrid crosses. (7) (b) What is meant by linkage? Explain with reference to chromosomal behaviour during meiosis? Q 6 (a) Explain complementation test and its applications in genetics. (5) (b) In Drosophila melanogaster, three recessive mutant genes, yellow body (v), white eye (w), and miniature wing (m) were studied using a three-point test cross. The following progeny were obtained ywm 350 Determine the order of these genes and the map distances between them. Calculate interference and write its significance. (5+2=7)